ISSN 2097-6054（网络） ISSN 1672-9234（印刷） CN 11-5289/R
主管：中国科学技术协会　主办：中华护理学会
出版：中华护理杂志社
收录：中国科学引文数据库（CSCD）来源期刊
　　　中国期刊全文数据库
　　　中国核心期刊（遴选）数据库
　　　Scopus
中华护理教育

中华护理教育 ›› 2026, Vol. 23 ›› Issue (4): 505-512.doi: 10.3761/j.issn.1672-9234.2026.04.019

• 专业实践研究 • 上一篇    

帕金森病患者体位性低血压管理内容的制订与实践研究

马雅英*(), 陈金花, 吴肖飞, 李晶, 郑枝燕, 孔雪   

  1. 浙江大学医学院附属第二医院神经内科 杭州市 310000
  • 收稿日期:2025-08-24 出版日期:2026-04-15 发布日期:2026-04-16
  • 通讯作者: *马雅英，女，本科，主管护师，E-mail：2508061@zju.edu.cn
  • 基金资助:
    浙江省医药卫生科技计划项目(2024KY1035)

Development and evaluation of a management content for orthostatic hypotension in Parkinson’s disease

MA Yaying*(), CHEN Jinhua, WU Xiaofei, LI Jing, ZHENG Zhiyan, KONG Xue   

  1. Neurological Department，the Second Affiliated Hospital Zhejiang University School of Medcine，Hangzhou 310000，China
  • Received:2025-08-24 Online:2026-04-15 Published:2026-04-16
  • Contact: *MA Yaying，E-mail：2508061@zju.edu.cn
  • Supported by:
    Medical and Health Science and Technology Program of Zhejiang Province(2024KY1035)

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摘要：

目的 构建帕金森病患者体位性低血压管理内容（简称内容）并评价其临床应用效果。 方法 通过文献研究和专家会议，形成内容初稿；对目的抽取的15名专家进行2轮函询，形成内容终稿。采用便利抽样法，选取2023年1月—12月收治于浙江省某三级甲等医院神经内科的110例帕金森病患者作为对照组，将2024年1月—12月该科收治的110例帕金森病患者纳入试验组。对照组接受常规护理，试验组接受基于内容的干预。比较护士对两组的体位性低血压的快速筛查率，干预4周后两组中伴体位性低血压患者直立症状严重程度、晨起卧立位血压差值、生活质量评分。 结果 护士对试验组体位性低血压的快速筛查率高于对照组（P<0.001）。干预4周后，试验组中伴体位性低血压患者六大直立症状严重程度评分、晨起卧立位收缩压差值和舒张压差值、生活质量评分均优于对照组中伴体位性低血压患者（均P<0.001）。 结论 内容具有科学性和可靠性，其应用可提高对帕金森病患者体位性低血压的规范管理水平，减轻伴体位性低血压的帕金森病患者直立症状严重程度，缩小其晨起卧立位血压差值，改善其生活质量。

关键词: 帕金森病, 体位性低血压, 管理内容, 构建, 应用, 德尔菲法

Abstract:

Objective To construct a management protocol for orthostatic hypotension in patients with Parkinson’s disease（hereinafter referred to as the content） and evaluate its clinical application effect. Methods The initial draft of the protocol was formulated through literature research and expert consultations. Two rounds of expert consultation were conducted among 15 purposively selected experts to finalize the content. By convenience sampling，110 patients with Parkinson’s disease admitted to the Department of Neurology of a Grade A tertiary hospital in Zhejiang Province from January to December 2023 were enrolled as the control group，and 110 patients with Parkinson’s disease admitted to the same department from January to December 2024 were enrolled as the experimental group. The control group received routine nursing care，while the experimental group received interventions based on the protocol. The two groups were compared in terms of the rapid screening rates of orthostatic hypotension，the severity of orthostatic symptoms，the difference in morning supine-standing blood pressure，and the quality of life scores of patients with orthostatic hypotension in both groups after 4 weeks of intervention. Results The nurses’ rapid screening rate of orthostatic hypotension by nurses in the experimental group was significantly higher than that in the control group（P<0.001）. After 4 weeks of intervention，the scores of the six major orthostatic symptoms，the differences in morning supine-standing systolic and diastolic blood pressure，and the quality of life scores of patients with orthostatic hypotension in the experimental group were all significantly better than those in the control group（all P<0.001）. Conclusion The protocol is scientific and reliable. Its application can improve the standardized management level of orthostatic hypotension in patients with Parkinson’s disease，alleviate the severity of patients’ orthostatic symptoms，reduce the morning supine-standing blood pressure difference，and improve patients’ quality of life.

Key words: Parkinson’s Disease, Orthostatic Hypotension, Management Content, Development, Application, Delphi Method