美国基因组护理学发展概况及启示

doi:10.3761/j.issn.1672-9234.2024.11.020

Abstract

Abstract:

Genomic nursing science is an important research direction of precision nursing. This article reviewed the concept，development，theoretical basis，research practice and education status of genomic nursing science in the United States and put forward the enlightenment for the development of interdisciplinary nursing in China. The aim of the article is to expanding the research field of interdisciplinary nursing，strengthening the diversification of nursing education and practice，and promoting innovation in nursing service models.

Key words: Precision nursing, Genomic nursing science, Nursing education, Interdisciplinary nursing

WANG Li, SUN Kaili, WU Qiwei, LIU Zuyun, ZHANG Huafang, YE Zhihong, SHAO Jing. Development of nursing genomic science in the United States and its enlightenment[J].Chinese Journal of Nursing Education, 2024, 21(11): 1397-1403.

References 56

[1]	中国学位与研究生教育学会. 研究生教育学科专业简介及其学位基本要求(试行版)[EB/OL]. [2024-07-11]. https://www.acge.org.cn/encyclopediaFront/enterEncyclopediaIndex.
[2]	李启杰, 陈雨文, 刘雨薇, 等. 全生命周期健康与疾病的精准护理研究现况与展望[J]. 四川大学学报(医学版), 2023, 54(4):705-711.
[3]	Williams JK, Katapodi MC, Starkweather A, et al. Advanced nursing practice and research contributions to precision medicine[J]. Nurs Outlook, 2016, 64(2):117-123. doi: S0029-6554(15)00324-3 pmid: 26712384
[4]	张格, 李燕, 孙盛楠, 等. 基因组护理学在肿瘤精准护理领域的应用与启示[J]. 中国护理管理, 2022, 22(12):1883-1887.
[5]	傅亮, 卢洪洲, 胡雁. 基因组护理学:现代护理学发展的动力[J]. 护理学杂志, 2014, 29(5):81-83.
[6]	Madden EB, Hindorff LA, Bonham VL, et al. Advancing genomics to improve health equity[J]. Nat Genet, 2024, 56(5):752-757. doi: 10.1038/s41588-024-01711-z pmid: 38684898
[7]	Schmauch E, Piening B, Mohebnasab M, et al. Integrative multi-omics profiling in human decedents receiving pig heart xenografts[J]. Nat Med, 2024, 30(5):1448-1460. doi: 10.1038/s41591-024-02972-1 pmid: 38760586
[8]	Regan M, Engler MB, Coleman B, et al. Establishing the genomic knowledge matrix for nursing science[J]. J Nurs Scholarsh, 2019, 51(1):50-57.
[9]	Wagner MA, Wesmiller SW, Maydick M, et al. Symptom science:omics and response to non-pharmacological interventions[J]. Biol Res Nurs, 2021, 23(3):394-401.
[10]	Tully LA, Calzone KA, Cashion AK. Establishing the omics nursing science & education network[J]. J Nurs Scholarsh, 2020, 52(2):192-200.
[11]	Landsberger BH, Landsberger HA. Health policy opinions of graduate students in nursing[J]. Int J Nurs Stud, 1986, 23(2):159-176. pmid: 3633878
[12]	Williams C. Teaching nursing homes:their impact on public policy,patient care,and medical education[J]. J Am Geriatr Soc, 1985, 33(3):189-195. pmid: 3973338
[13]	常承婷, 刘雨薇, 田亚丽, 等. 精准护理的研究进展[J]. 中国科学:生命科学, 2022, 52(11):1731-1737.
[14]	Gibbs RA. The human genome project changed everything[J]. Nat Rev Genet, 2020, 21(10):575-576. doi: 10.1038/s41576-020-0275-3 pmid: 32770171
[15]	Collins FS, Varmus H. A new initiative on precision medicine[J]. N Engl J Med, 2015, 372(9):793-795.
[16]	Hickey KT, Bakken S, Byrne MW, et al. Precision health:advancing symptom and self-management science[J]. Nurs Outlook, 2019, 67(4):462-475.
[17]	Hacker ED, McCarthy AM, DeVon H. Precision health:emerging science for nursing research[J]. Nurs Outlook, 2019, 67(4):287-289. doi: 10.1016/j.outlook.2019.06.008
[18]	Fu MR, 田亚丽, 胡秀英, 等. 精准护理的应用领域及发展方向[J]. 中华护理杂志, 2017, 52(10):1273-1275.
[19]	广东省精准医学应用学会. 广东省精准医学应用学会团体标准精准护理体系[S]. 2020.
[20]	Genomic Nursing State of the Science Advisory Panel,Calzone KA, Jenkins J, et al. A blueprint for genomic nursing science[J]. J Nurs Scholarsh, 2013, 45(1):96-104.
[21]	National Human Genome Research Institute. Genomic Nursing Science Blueprint:next steps meeting summary[EB/OL]. (2014-08-28)[2024-07-11]. https://www.genome.gov/Pages/Health/HealthCareProvidersInfo/Genomic_Nursing_Science_Blueprint_Report_102414.pdf.
[22]	Cashion AK, Grady PA. The National Institutes of Health/National Institutes of Nursing Research intramural research program and the development of the National Institutes of Health Symptom Science Model[J]. Nurs Outlook, 2015, 63(4):484-487. doi: 10.1016/j.outlook.2015.03.001 pmid: 26187087
[23]	Kurnat-Thoma EL, Graves LY, Billones RR. A concept development for the symptom science model 2.0[J]. Nurs Res, 2022, 71(6):E48-E60.
[24]	苏晓雨, 王青青, 刘风侠. 肿瘤患者症状群生物学机制的研究进展[J]. 癌症进展, 2022, 20(6):555-558,572.
[25]	Mirzaei S, Burke L, Rosenfeld AG, et al. Protein cytokines,cytokine gene polymorphisms,and potential acute coronary syndrome symptoms[J]. Biol Res Nurs, 2019, 21(5):552-563.
[26]	Martin C, Cho YE, Kim H, et al. Altered DNA methylation patterns associated with clinically relevant increases in PTSD symptoms and PTSD symptom profiles in military personnel[J]. Biol Res Nurs, 2018, 20(3):352-358. doi: 10.1177/1099800418758951 pmid: 29514460
[27]	An K, Starkweather A, Sturgill J, et al. Association of CTRP13 with liver enzymes and cognitive symptoms in nonalcoholic fatty liver disease[J]. Nurs Res, 2019, 68(1):29-38. doi: 10.1097/NNR.0000000000000319 pmid: 30247335
[28]	National Academies of Sciences,Engineering,and Medicine;National Academy of Medicine;Committee on the Future of Nursing 2020-2030. The future of nursing 2020-2030:charting a path to achieve health equity[M]. Washington(DC): National Academies Press(US), 2021.
[29]	Liu ZY, Kuo PL, Horvath S, et al. A new aging measure cap-tures morbidity and mortality risk across diverse subpopulations from NHANES Ⅳ:a cohort study[J]. PLoS Med, 2018, 15(12):e1002718.
[30]	Graf GH, Crowe CL, Kothari M, et al. Testing black-white disparities in biological aging among older adults in the United States:analysis of DNA-methylation and blood-chemistry methods[J]. Am J Epidemiol, 2022, 191(4):613-625.
[31]	Gao X, Geng T, Jiang MJ, et al. Accelerated biological aging and risk of depression and anxiety:evidence from 424 299 UK biobank participants[J]. Nat Commun, 2023, 14(1):2277. doi: 10.1038/s41467-023-38013-7 pmid: 37080981
[32]	Carugno M, Maggioni C, Crespi E, et al. Night shift work,DNA methylation and telomere length:an investigation on hospital female nurses[J]. Int J Environ Res Public Health, 2019, 16(13):2292.
[33]	肇丽梅. 临床药物个体化治疗[J]. 药学进展, 2020, 44(6):401-403.
[34]	Lu YX, Karagounis LG, Ng TP, et al. Systemic and metabolic signature of sarcopenia in community-dwelling older adults[J]. J Gerontol A Biol Sci Med Sci, 2020, 75(2):309-317.
[35]	Janzen DM, Rosales MA, Paik DY, et al. Progesterone receptor signaling in the microenvironment of endometrial cancer influences its response to hormonal therapy[J]. Cancer Res, 2013, 73(15):4697-4710. doi: 10.1158/0008-5472.CAN-13-0930 pmid: 23744837
[36]	Mathew A, Doorenbos AZ, Vincent C. Symptom management theory:analysis,evaluation,and implications for caring for adults with cancer[J]. ANS Adv Nurs Sci, 2021, 44(3):E93-E112.
[37]	Martin CA, Vorn R, Schrieber M, et al. Identification of DNA methylation changes that predict onset of post-traumatic stress disorder and depression following physical trauma[J]. Front Neurosci, 2021,15:738347.
[38]	Sealschott S, Pickler R, Fortney C, et al. Gut microbiota and symptom expression and severity in neonatal abstinence syndrome[J]. Biol Res Nurs, 2024, 26(3):460-468. doi: 10.1177/10998004241242102 pmid: 38528812
[39]	Grady PA, Collins FS. Genetics and nursing science:realizing the potential[J]. Nurs Res, 2003, 52(2):69.
[40]	Jenkins J, Grady PA, Collins FS. Nurses and the genomic revolution[J]. J Nurs Scholarsh, 2005, 37(2):98-101.
[41]	American Nurses Association, Consensus Panel on Genetic/Ge-nomic Nursing Competencies. Essentials of genetic and ge-nomic nursing:competencies,curricula guidelines,and outcome indicators,2nd edition[EB/OL]. (2011-07-12) [2024-07-11]. https://repository.library.georgetown.edu/handle/10822/514214?show=full.
[42]	Forsman I. Education of nurses in genetics[J]. Am J Hum Genet, 1988, 43(4):552-558. pmid: 3177390
[43]	American Nurse Accreditation Center. Advanced genetics nurs-ing certification(AGN-BC)[EB/OL]. (2023-05-01)[2024-07-11]. https://www.nursingworld.org/our-certifications/advanced-genetics-nursing-renewal/.
[44]	American Association of Colleges of Nursing. The research-focused doctoral program in nursing:pathways to excellence[EB/OL]. [2024-07-11]. https://www.aacnnursing.org/news-data/position-statements-white-papers/research-focused-pathways-to-excellence.
[45]	Fairman JA, Giordano NA, McCauley K, et al. Invitational summit:re-envisioning research focused PHD programs of the future[J]. J Prof Nurs, 2021, 37(1):221-227. doi: 10.1016/j.profnurs.2020.09.004 pmid: 33674099
[46]	Tubbs-Cooley HL, Lavin R, Lyndon A, et al. Stronger together:the case for multidisciplinary tenure track faculty in academic nursing[J]. Nurs Outlook, 2021, 69(4):531-533.
[47]	National Institute of Nursing Research. Apply to NINR’s Sum-mer Genetics Institute(SGI) by March 1[EB/OL]. (2020-02-14)[2024-07-11]. https://www.ninr.nih.gov/newsandevents/news/closing-soon-apply-ninrs-summer-genetics-institute-sgi-march-1-0.
[48]	Yang I, Holstad M. Proceedings of the summer institute on symptoms and omics[J]. Biol Res Nurs, 2022, 24(1):5-9.
[49]	American Association of Colleges of Nursing. The essentials:core competencies for professionals nursing education[EB/OL]. [2024-07-11]. https://www.aacnnursing.org/Portals/0/PDFs/Publications/Essentials-2021.pdf.
[50]	教育部. 教育部关于公布2023年度普通高等学校本科专业备案和审批结果的通知[EB/OL].[2024-07-11]. https://www.gov.cn/zhengce/zhengceku/202403/content_6940137.htm.
[51]	李进, 冯先琼. 本科护理课程体系引入《护理遗传学与基因组学》的实践探索[J]. 中国实用护理杂志, 2016, 32(13):1031-1033.
[52]	浙江大学社会科学研究院. 社科院关于申报2023年浙江大学学科交叉预研专项项目的通知[EB/OL]. (2023-02-27)[2024-07-11]. https://rwsk.zju.edu.cn/2023/0227/c40200a2721108/page.htm.
[53]	浙江在线. 遗传专科护士来了[EB/OL].(2022-08-20)[2024-07-12]. http://media.zjol.com.cn/jiankang/202208/t20220820_24687350.shtml.
[54]	陈东亮, 王媛飞, 陆晓敏, 等. 症状科学模型在慢性病护理中的应用进展及启示[J]. 中华护理杂志, 2023, 58(6):751-757. doi: 10.3761/j.issn.0254-1769.2023.06.016
[55]	Tian M, Liu H, Chen SL, et al. Report on the 3rd board meeting of the international human phenome consortium[J]. Phenomics, 2023, 3(1):77-82.
[56]	National Institute of Nursing Research. The National Institute of Nursing Research 2022-2026 strategic plan[EB/OL]. [2024-07-11]. https://www.ninr.nih.gov/sites/default/files/docs/NINR_StratPlan-FactSheet07302024_508c.pdf.

Development of nursing genomic science in the United States and its enlightenment

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