Objective To systematically evaluate the effects of electronic health cardiac rehabilitation program on patients with coronary heart disease. Methods Comprehensive search was conducted in PubMed,Embase,Web of Science,Cochrane,Springer,ScienceDirect,Ovid,EBSCO,CBM,CNKI,Wanfang,and VIP,supplemented by manual search. The search time limit was form inception to April 2020. The effects of heart rehabilitation was determined by mata-analysis with Stata 14.0 after data extraction and quality appraisal. Results A total of 14 studies were included. Compared with the control group,the electronic health-based cardiac rehabilitation program could improve the time of physical activity(SMD=0.24,95%CI=0.04~0.45,P=0.02),daily steps(SMD=0.41,95%CI=0.22~0.60,P<0.001),the quality of life(SMD=0.97,95%CI=0.12~1.81,P=0.02),and reduce the readmission rate(RR=0.49,95%CI=0.27~0.89,P=0.02). Sensitivity analysis found that cardiac rehabilitation based on electronic health could effectively improve eating habits(SMD=0.49,95%CI=0.15~0.83,P=0.005),total cholesterol level(SMD=-0.23,95%CI=-0.41~-0.04,P=0.02),and low-density lipoprotein(SMD=-0.36,95%CI=-0.55~-0.17,P<0.001). Conclusion Cardiac rehabilitation based on electronic health can effectively improve patients’ enthusiasm for sustaining a good lifestyle,improving their eating habits,and quality of life,reducing their total cholesterol and low-density lipoprotein levels,and the readmission rate.