Objective To explore the effects of the maker education in assisted teaching practice of Surgical Nursing in undergraduates. Methods Students in two classes were randomly selected and assigned to the experimental group or the control group. Maker education was carried out in 54 students of the experimental group. Contents of the maker education were consisted of 7 aspects including story introduction,simple task simulation,key points explanation,comprehensive task simulation,innovation guidance,task completion,and works demonstration. The 52 students in the control group were guided to practice the skills in the lab room. Contents included teaching,group practice,tour teaching,assessment,and summary. At the end of the course,two groups of students were assessed for their practical skills. Besides,the Test of Creative Imagination and the evaluation form were used to evaluate the effects of the maker education. Results There was no statistically significant difference in the skill performance of students in two groups(P>0.05). The creative thinking score of students in the experimental group was higher than that of the control group(P<0.05). Students in the experimental group gave an average score of(4.18±0.13) for their teaching evaluation. Conclusion Maker education can improve the creative thinking of nursing undergraduates,and the method is also recognized by most students.