To effectively implement the “Guideline for Ideological and Political Education of Nursing Professional Courses” and to guide the development of ideological and political education in nursing professional courses in colleges and universities across the country,the Guiding Committee of Nursing Professional Teaching in Colleges and Universities of the Ministry of Education developed the “Guideline for Ideological and Political Education of Nursing Professional Courses”(“Guideline” was used in the following part) according to the requirements of the Higher Education Department of the Ministry of Education. In this paper,we interpreted the contents of each part of the Guideline and the key points during the implementation. The interpretation is believed to help majority of nursing teachers and administrators better use this Guideline in nursing professional education and teaching,and combine ideological and political teaching with professional teaching to cultivate high-quality nursing talents.