Abstract: Objective To investigate the effects of staged antiemetic care on prevention of chemotherapy induced nausea and vomiting（CINV） of cancer patients. Methods A total of 120 patients with nausea，vomiting and retching caused by chemotherapy were chosen by convenience sampling，and were evenly divided into the experimental group （60 patients） and the control group （60 patients）. Patients in the experimental group received staged antiemetic care including pre-treatment prevention，mid-term care，and followed assessment to manage the adverse reactions of chemotherapy in patients. Patients in the control group received routine care. Results After 4 cycles of chemotherapy，the frequency，severity and duration of nausea，vomiting and retching in the experimental group
were improved greater than those in the control group（P<0.05）. Conclusion The staged antiemetic care can effectively improve the quality of life of patients and reduce the occurrence of CINV.