癌症患者衰弱筛查工具的质量评价

doi:10.3761/j.issn.1672-9234.2023.10.016

摘要/Abstract

摘要：

目的描述和评价癌症患者衰弱筛查工具的测量属性，为医护人员及研究者选择筛查工具提供参考依据。方法检索中国知网、万方数据库、维普数据库、PubMed、Embase（Ovid）、CENTRAL、CINAHL、Web of Science、Scopus、PsycINFO，检索时限为建库至2022年5月24日，纳入开发或验证癌症患者衰弱筛查工具的研究。由2名研究人员独立进行文献筛选与资料提取，采用基于共识的健康测量工具选择标准指南中的偏倚风险评估清单、质量准则对纳入研究的方法学质量及工具的测量属性进行系统评价，应用改良版证据质量评价及推荐强度评级指南进行证据质量分级，并结合筛查工具的应用性评价，形成最终推荐意见。结果共纳入19项研究，涉及16种癌症患者特异性衰弱筛查工具。所有工具均未进行跨文化效度/测量不变性、效标效度、测量误差和反应度测评。纳入工具的证据质量等级均为“中”或“低”，均为B类推荐。老年筛查工具-8和简化版老年综合评估是被验证次数较多的工具。结论癌症患者衰弱筛查工具多样但质量整体不高。老年筛查工具-8和简化版老年综合评估在应用潜力上相对良好，可暂时推荐使用。未来仍需进一步验证性能，并引进和发展本土化癌症患者衰弱筛查工具。

关键词: 癌症, 衰弱, 筛查工具, 测量属性, 质量评价

Abstract:

Objectives To describe and evaluate the measurement properties of screening tools assessing the frailty for cancer patients，and to provide a reference for selecting screening tools. Methods CNKI，Wanfang database，VIP，PubMed，Embase（Ovid），CENTRAL，CINAHL，Web of Science，Scopus，PsycINFO databases were electronically searched to collect studies on the screening tools of assessing the frailty in cancer patients from their inception to May 24，2022. Two researchers screened articles and extracted data independently. Consensus-based Standards for the selection of health Measurement Instruments （COSMIN） risk of bias checklist and quality criteria were used to assess the methodological quality of the included studies and the measurement properties of the screening tools. The evidence rating of each measurement properties of the screening tools was evaluated by the modified grading of recommendation assessment，development of evaluation （GRADE），and the final recommendations were formulated based on the application evaluation of the screening tools. Results A total of 19 studies involving sixteen screening tools were included. None of the included screening tools was assessed cross-cultural validity/measurement invariance，criterion validity，measurement error or responsiveness. The included instruments were all rated as "moderate" or "low" in terms of quality of evidence and all tools’ level were B. The Geriatric-8 and abbreviated Comprehensive Geriatric Assessment were the more frequently validated tools. Conclusion The screening tools assessing frailty for cancer patients are diverse，but the overall quality of evidence is not high. The Geriatric-8 and abbreviated Comprehensive Geriatric Assessment have relatively good application potential and can be temporarily recommended for use. In the future，it is still necessary to further validate the properties，and introduce and develop localized frailty screening tools for cancer patients.

Key words: Cancer, Frailty, Screening tools, Measurement properties, Quality appraisal

梁冉, 江琪, 石佳景, 黄铮, 方一芳, 吴炜炜. 癌症患者衰弱筛查工具的质量评价[J]. 中华护理教育, 2023, 20(10): 1245-1252.

LIANG Ran, JIANG Qi, SHI Jiajing, HUANG Zheng, FANG Yifang, WU Weiwei. Quality appraisal of the frailty screening tools for cancer patients[J]. Chinese Journal of Nursing Education, 2023, 20(10): 1245-1252.

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