非酒精性脂肪性肝病非药物管理的证据总结

doi:10.3761/j.issn.1672-9234.2025.09.017

Abstract

Abstract:

Objective To summarize the best evidence for non-pharmacological management of patients with non-alcoholic fatty liver disease（NAFLD）. Methods A systematic search was conducted across decision support systems，Chinese and English databases，guideline websites，and professional society websites for literature on non-pharmacological management of NAFLD from inception to May 1，2025. After independent literature screening，data extraction，and methodological quality assessment by two researchers trained in evidence-based nursing，the evidence was extracted，graded，and synthesized. Results A total of 24 literature were included，comprising 11 guidelines，eight expert consensus statements，and five systematic reviews. These yielded 34 best evidence items categorized into four domains：support and follow-up management，weight management，dietary management，and exercise management. Conclusion This study consolidates the best evidence for non-pharmacological management of NAFLD，which can offer an evidence-based foundation for delivering individualized lifestyle guidance to patients.

Key words: Non-alcoholic fatty liver disease, Non-pharmacological management, Evidence summary, Evidence-based nursing

SHENG Guixiao, SANG Ming, MEI Binbin, YANG Liping. Evidence summary for non-pharmacological management of non-alcoholic fatty liver disease[J].Chinese Journal of Nursing Education, 2025, 22(9): 1133-1140.

Figures/Tables 4

References 46

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Evidence summary for non-pharmacological management of non-alcoholic fatty liver disease

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