Objective To investigate the current status and influencing factors of kinesiophobia in breast cancer patients with implantable venous access ports（IVAP）. Methods From August to December 2024，a convenience sampling method was used to recruit breast cancer patients undergoing chemotherapy with IVAP implantation in the Department of Thyroid and Breast Surgery of a Grade A Class Ⅲ hospital in Beijing. Participants were assessed by a General Information Questionnaire，the Tampa Scale of Kinesiophobia（TSK），and the Cancer Patients TIVAPs Self-Management Scale. Results The mean kinesiophobia score among 194 breast cancer patients with IVAP was （44.02±4.72），with an incidence rate of 85.6%. Multivariate linear regression analysis revealed that a number of factors significantly influenced kinesiophobia （P<0.05） including educational level （junior high school or below，and college/undergraduate，with “postgraduate” as the reference）；duration of IVAP application（3-6 months，with “<3 months” as the reference）；exercise habits；familiarity with IVAP （very familiar，with “unfamiliar” as the reference）；and self-management behavior level related to IVAP. These variables collectively explained 66.6% of the variance in kinesiophobia among the patients. Conclusion Breast cancer patients with IVAP exhibit a high incidence of kinesiophobia，influenced by multiple factors. Healthcare providers should prioritize early identification of kinesiophobia in this population and implement targeted interventions to reduce fear of movement，so as to enhance physical activity engagement and facilitate rehabilitation.