Objective To design a teaching plan for the Humanistic Care in Nursing courses in undergraduate education and evaluate the effects of its application. Methods A teaching scheme for the Humanistic Care in Nursing courses was developed，which mainly included clarifying teaching objectives，integrating and optimizing teaching content，advancing teaching implementation，constructing teaching resources，and designing teaching evaluation. This scheme was applied to the nursing students enrolled in 2022 and 2023 academic years at our college. The teaching effects were evaluated through course grades，visual practice works on humanistic care，and semi-structured interviews with students. Results The course grades of 194 nursing undergraduate students averaged at（92±3） points，and a total of 20 visual practice works on humanistic care were produced. Through analyzing the interview data，five themes were extracted：creating a friendly and interactive scenario to promote deep interpersonal communication； improving students’ classroom participation，strengthening their status as the main body and engagement，and promoting the development of their academic literacy； helping students understand the essence of care and practice it，achieving the transfer and transformation of knowledge； facilitating the development of students’ comprehensive abilities； enhancing the effects of ideological and political education，and contributing to the cultivation of nursing talents with both ability and moral integrity. Conclusion The teaching of the Humanistic Care in Nursing courses in undergraduate education achieves good results，which effectively improving students’ practical ability in humanistic care and their level of humanistic literacy. Students have a high degree of recognition for this course.