Objective To evaluate and summarize the relevant evidence of the prevention of tracheostomy-related pressure injury（TRPI） in adults，and to provide references for clinical practice. Methods We searched for clinical decisions，guidelines，recommended practices，evidence summaries，expert consensuses and other evidence on the prevention of TRPI in the UpToDate，BMJ Best Practice，Joanna Briggs Institute Library，Guidelines International Network，National Guideline Clearinghouse，Registered Nurses’ Association of Ontario，Society of Critical Care Medicine，European Pressure Ulcer Advisory Panel，National Pressure Injury Advisory Panel，Cochrane Library，PubMed，CNKI，Wanfang Data etc. Results A total of 15 articles were incorporated，including 2 clinical decisions， 8 guidelines，2 evidence summaries，1 recommended practice，2 expert consensuses. Thirty-two pieces of the best evidence were summarized in 7 aspects，namely risk assessment，skin assessment，selection and application of tracheal cannula and tapes，selection and application of preventive dressings，skin care，nutrition assessment and support，organization management and education training. Conclusion Clinical institutions and medical staffs should evaluate factors such as the medical environment，cost of consumables，and patients’ willingness，and combine with the best evidence to implement preventive strategies in a standardized manner，and ultimately reduce the occurrence of TRPI.