eISSN 2097-6054 ISSN 1672-9234 CN 11-5289/R
Responsible Institution：China Association for Science and Technology
Publishing:Chinese Nursing Journals Publishing House Co.,Ltd.
Sponsor：Chinese Nursing Association
Source journal for Chinese Science Citation Database
China Academic Journals Full-text Database
China Core Journal Alternative Database
Scopus
Chinese Journal of Nursing Education

Chinese Journal of Nursing Education >

2022 , Vol. 19 >Issue 10: 938 - 943

DOI: https://doi.org/10.3761/j.issn.1672-9234.2022.10.014

Clinical Practice

A systematic review of the effects of the comprehensive intervention on frailty in older population

  • Xuya HAN ,
  • Li TIAN ,
  • Dan LÜ ,
  • Ting CAO ,
  • Changlian CHEN ,
  • Jiayan CAO
Expand

Received date: 2021-10-18

  Online published: 2022-10-25

Fold

Abstract

Objective To identify the effects of the comprehensive intervention on frailty in older population through meta-analysis. Methods Randomized controlled trials on the effectiveness of the comprehensive intervention on frailty of older population were retrieved from the electronic databases of Cochrane Library,PubMed,Embase,Web of Science,CINAHL,CNKI,CBM,Wanfang and VIP from January 2010 to December 2020. Results A total of 11 articles involving 2 714 old people were finally included. Meta-analysis results showed that the comprehensive intervention had a positive effect on gait speed[SMD=0.13,95%CI（0.03,0.22）,P=0.007],Barthel Index[WMD=2.52,95%CI（0.81,4.23）,P=0.004] and depression [SMD=-0.09,95%CI（-0.18,-0.00）,P=0.04]. The comprehensive intervention had no significant effects on frailty score[WMD=-0.12,95%CI（-0.43,0.18）,P=0.42],grip strength [WMD=1.35,95%CI（-0.92,3.61）,P=0.24] and quality of life in older population[WMD=-0.42,95%CI（-0.97,0.13）,P=0.13]. Conclusion The comprehensive intervention significantly improves the gait speed,Barthel Index and depression,but cannot improve frailty score,grip strength and quality of life. At present,the evidence on the effects of the comprehensive intervention on frailty in older population is still insufficient. There are many differences among studies. More high-quality studies are needed to verify the effects of the comprehensive intervention on frailty in older adults.

Key words： Aged; Frailty; Comprehensive intervention; Systematic review

Cite this article

Xuya HAN , Li TIAN , Dan LÜ , Ting CAO , Changlian CHEN , Jiayan CAO . A systematic review of the effects of the comprehensive intervention on frailty in older population[J]. Chinese Journal of Nursing Education, 2022 , 19(10) : 938 -943 . DOI: 10.3761/j.issn.1672-9234.2022.10.014

References

[1] Fried LP, Tangen CM, Walston J, et al. Frailty in older adults:evidence for a phenotype[J]. J Gerontol A Biol Sci Med Sci, 2001, 56(3):146-156.
[2] Fairhall N, Aggar C, Kurrle SE, et al. Frailty intervention trial(FIT)[J]. BMC Geriatr, 2008, 8:27.
[3] Dent E, Lien C, Lim WS, et al. The Asia-Pacific clinical practice guidelines for the management of frailty[J]. J Am Med Dir Assoc, 2017, 18(7):564-575.
[4] Ruiz JG, Dent E, Morley JE, et al. Screening for and managing the person with frailty in primary care:ICFSR consensus guidelines[J]. J Nutr Health Aging, 2020, 24(9):920-927.
[5] Li CM, Chen CY, Li CY, et al. The effectiveness of a comprehensive geriatric assessment intervention program for frailty in community-dwelling older people:a randomized,controlled trial[J]. Arch Gerontol Geriatr, 2010, 50:39-42.
[6] Cameron ID, Fairhall N, Langron C, et al. A multifactorial interdisciplinary intervention reduces frailty in older people:randomized trial[J]. BMC Med, 2013, 11:65.
[7] Fairhall N, Sherrington C, Lord SR, et al. Effect of a multifactorial,interdisciplinary intervention on risk factors for falls and fall rate in frail older people:a randomised controlled trial[J]. Age Ageing, 2014, 43(5):616-622.
[8] Fairhall N, Sherrington C, Kurrle SE, et al. Economic evaluation of a multifactorial,interdisciplinary intervention versus usual care to reduce frailty in frail older people[J]. J Am Med Dir Assoc, 2015, 16(1):41-48.
[9] Ng TP, Feng L, Nyunt MSZ, et al. Nutritional,physical,cognitive,and combination interventions and frailty reversal among older adults:a randomized controlled trial[J]. Am J Med, 2015, 128(11):1225-1236.
[10] Ng TP, Nyunt MSZ, Feng L, et al. Multi-domains lifestyle interventions reduces depressive symptoms among frail and pre-frail older persons:randomized controlled trial[J]. J Nutr Health Aging, 2017, 21(8):918-926.
[11] Andrieu S, Guyonnet S, Coley N, et al. Effect of long-term omega 3 polyunsaturated fatty acid supplementation with or without multidomain intervention on cognitive function in elderly adults with memory complaints(MAPT):a randomised,placebo-controlled trial[J]. Lancet Neurol, 2017, 16(5):377-389.
[12] Gené Huguet L, Navarro González M, Kostov B, et al. Pre frail 80:multifactorial intervention to prevent progression of pre-frailty to frailty in the elderly[J]. J Nutr Health Aging, 2018, 22(10):1266-1274.
[13] Romera-Liebana L, Orfila F, Segura JM, et al. Effects of a pri-mary care-based multifactorial intervention on physical and cognitive function in frail,elderly individuals:a randomized controlled trial[J]. J Gerontol A Biol Sci Med Sci, 2018, 73(12):1688-1674.
[14] 倪洁, 葛兆霞. 衰弱前期老年患者运动衰弱干预试验效果观察[J]. 护理学报, 2019, 26(15):65-69.
[14] Ni J, Ge ZX. Observation on the effect of exercise intervention experiment on elderly patients with prefrail[J]. J Nurs (China), 2019, 26(15):65-69.
[15] Chen LK, Hwang AC, Lee WJ, et al. Efficacy of multidomain interventions to improve physical frailty,depression and cognition:data from cluster-randomized controlled trials[J]. J Cachexia Sarcopenia Muscle, 2020, 11:650-662.
[16] 曹亭, 刘启帆, 施月仙, 等. 运动联合营养支持对衰弱期及衰弱前期老年人影响的Meta分析[J]. 中国护理管理, 2019, 19(1):52-59.
[16] Cao T, Liu QF, Shi YX, et al. Effects of exercise combined with nutrition support on the elderly with frailty or pre-frailty:a Meta-analysis[J]. Chin Nurs Manag, 2019, 19(1):52-59.
Options
Outlines

/

〈 〉