Objective To explore the effects of online teaching of Nursing Aesthetics in a higher vocational college. Methods The teaching team was established and online contents was developed. Besides,the online teaching activities were also designed. Based on a learning and education platform,365 nursing students in a higher vocational college were taught online. Students examination performance and online learning data were assessed. Results The final examination score of students was（87.12±3.67）. The average completion rate of video watching was 98.8%,the average rate of attendance was 95.5%,the average number of online discussions was 22.9,and the completion rate of homework after class was 96.3%. Conclusion Students’ final examination scores and class participation are acceptable.