Objective To explore the effects of anesthesia nurses training.Methods A total of 101 trainees from 48 medical consortiums in our province were trained based on the core competence,contents of the training included knowledge education and clinical practice. The effectiveness of the training was evaluated by the score of core competence,theoretical knowledge,and operational skills.Results The scores of the 101 anesthesiologists were（125.57±4.80）before the training and（156.45±4.39）after the training（P<0.05）. The average scores of the theoretical knowledge and skills were（88.76±2.34）and（86.68±3.46）respectively. The satisfaction score of trainees with the training system was（4.89±0.34）.Conclusion Through the training of anesthesia nurses,the core competence of anesthesia nurses has been improved,and the theoretical knowledge and clinical skills of trainees have been consolidated.