Objective To collect and summarize the evidence based clinical practice of medical device related pressure injury prevention. Methods We searched related studies regarding the prevention of medical device related pressure injury in main databases from inception to October 2019. Two investigators evaluated the quality of the included literatures by using the literature evaluation criteria and evidence classification system of the Joanna Briggs Institute and extracted evidences from documents that met the inclusion criteria. Results A total of 8 articles were included with 6 guidelines,1 expert consensus,and 1 systematic review. The best evidence included skin assessment,skin cleaning,placement and movement of medical devices,rational use of dressings,and education and training. Conclusion This study summarizes the evidence based clinical practice for preventing medical device related pressure injury by searching databases at home and abroad. It is suggested that evidence users should select best evidence with consideration of hospital characteristics,clinical settings,promoting and hindering factors by medical staffs and the willingness of patients. The study can provide more evidence for clinical practice so as to improve the quality of nursing.