Objective To explore the effects of a pressure injury management strategy by the wound ostomy specialty nurses. Methods We firstly analyzed the pressure injury management needs in our hospital. Then the management strategy of pressure injury which was led by the wound ostomy specialty nurses was developed and constructed. These strategies included personnel selection，team construction，making good use of the functions of specialty nurses，management process standardization，and establishing the monitoring system of pressure injury. Results There was a significant difference in qualification rate of the theory and skill assessments regarding the pressure injury management（P<0.01）. The incidence of stress injury in our hospital decreased year by year from 2016 to 2018（P<0.01）. Conclusion The pressure injury management model can make the wound ostomy specialty nurses play their roles completely. The model can improve the abilities of wound ostomy specialty nurses，decrease the incidence of pressure injury，relieve the sufferings of patients，and increase the social benefits of the hospital.