目的 探讨愉快因子刺激联合兴趣激励疗法对脑卒后抑郁患者的抑郁程度及神经功能康复的影响。方法 选取2015年12月—2016年7月所有入住福建中医药大学附属康复医院神经康复科的脑卒中抑郁患者,将符合纳入和排除标准的一病区63例患者设为试验组,二病区的32例患者设为对照组,对照组给予常规治疗和护理,试验组在常规治疗和护理的基础上予以愉快因子刺激和兴趣激励疗法,内容包括与患者进行交谈,开展书画、唱歌、讲故事、抛接球等活动。两组各干预4周,分别在护理干预前、治疗4周后应用汉密尔顿抑郁量表和改良的Barthel指数进行评价。 结果 试验组患者抑郁改善情况及日常生活能力优于对照组（P<0.05）。结论 愉快因子刺激联合兴趣激励疗法可以改善患者的抑郁症状,提高患者的日常生活活动能力。

Objective To explore the effects of jolly factor together with interest motivation on depression of post-stroke patients. Methods A total of 63 eligible post-stroke patients with depression were recruited from December 2015 to July 2016 in rehabilitation department of the Rehabilitation Hospital which is affiliated to the Fujian University of Traditional Chinese Medicine. Patients were recruited according to the inclusion and exclusion criteria. Thirty-one patients in Ward Ⅰ were in the experiental group,while 32 patients in Ward Ⅱ were in the control group. Both groups received routine therapy and care. Patients in the experimental group received the intervention of jolly factor together with interest motivation. Contents of the intervention included chatting with the patients,participating some activities such as handwriting,singing,storytelling,and throwing and catching balls. The Hamilton Depression Scale（HAMD） and Modified Barthel Index（MBI） were used to evaluate patients’ depression level before the intervention and 4 weeks after the intervention. Results The depression level and daily activity level of patients in the experimental group were significantly higher than those of patients in the control group（P<0.05）. Conclusion Jolly factors together with interest activation can alleviate depression level of post-stroke patients and improve their activities of daily living.