目的  探讨健康教育对性病患者疾病相关知识掌握及安全性行为的影响。 方法  对7名专职宣教护士进行专业知识及技能培训，培训后护士在“悄悄话诊室”对362例患者进行一对一的性病相关知识教育、健康性行为指导、加强心理干预及随访等。结果  干预后患者对疾病复发相关知识、危险因素、预防常识和严重后果的知识掌握率显著提高（P＜0.01）；性行为时每次使用安全套意愿从干预前的8.01%提高到干预后的51.66%，选择配偶的比例从15.19%提高到40.88%，选择固定性伴的比例从23.48%提高到33.98%，与交易性伴发生性关系的比例从31.49%降低至11.05%，干预前后比较，差异有统计学意义（P＜0.01）。 结论  对性病患者实施健康教育，可有效提高性病患者对性病相关知识的认知，促进其高危行为的改变和安全套的使用。

Objective  To evaluate the effect of health education on disease-related knowledge and safe sex in patients with sexually transmitted diseases（STD）. Methods  Seven nurses received professional knowledge and skills training and they provided health education on STD-related knowledge and safe sex，psychological interventions and follow-up service for 362 STD patients in the private consulting room. Results  After intervention，the patients?蒺 knowledge related to the relapse，risk factors，prevention and consequences of STD increased significantly（P<0.01）；their willingness to use condoms increased from 8.01% to 51.66%；the proportion having sex behaviors with spouse increased from 15.19% to 40.88%，with regular sex partner increased from 23.48% to 33.98%，with commercial partners decreased from 31.49% to 11.05%（P<0.01）. Conclusion  Health education can effectively improve the disease-related knowledge and promote safe sex behaviors in STD patients.