目的 探讨猪肺模拟仿生模拟系统在急诊科低年资护士呼吸机应用培训中的实施路径与初步成效。 方法 针对某公立三级甲等医院急诊科22名低年资护士开展呼吸机应用培训，使用离体猪肺制作呼吸机仿生模拟系统作为辅助教学工具，将其连接于呼吸机上进行模拟演示与案例教学。分别于培训前（T0）、理论培训后（T1）及猪肺仿生模拟培训后（T2）3个时间点对学员进行测评，包括理论测试、操作能力测试及中文版护士专业自我效能感量表测评，使用单因素重复测量方差分析进行统计学分析。 结果 3个时间点学员的理论测试、操作能力测试及自我效能感得分均存在显著效应（F=30.791，P<0.001；F=57.460，P<0.001；F=230.156，P<0.001）。进一步两两比较结果显示，学员在T1和T2的各项指标得分均高于T0（P<0.05），且学员在T2的操作能力测试和自我效能感得分高于T1（P<0.05）。 结论 将离体猪肺应用于急诊科呼吸机应用培训中，有助于学员直观理解呼吸机应用的理论知识，促进其操作能力和自我效能的提升，可为优化急诊科护士培训方案提供参考。

Objective To evaluate the effectiveness of a porcine lung-based bionic simulation system in mechanical ventilator training for junior nurses in the emergency department. Methods The ventilator application training was conducted for 22 junior nurses in the emergency department of a public tertiary hospital. An ex-vivo porcine lung was used to create a bionic teaching tool connected to a ventilator for simulated demonstrations and case-based instruction. Assessments were conducted on the trainees at three time points：before training（T0），after theoretical training（T1），and after porcine lung simulation training （T2）. Assessments included theoretical knowledge tests，operational skills tests，and the Chinese version of the Nurses’ Professional Self-Efficacy Scale. Statistical analysis was performed using one-way repeated-measures ANOVA. Results Significant differences were observed across the three time points in trainees’ scores for theoretical knowledge（F=30.791，P<0.001），operational skills（F=57.460，P<0.001），and self-efficacy（F=230.156，P<0.001）. Further pairwise comparisons revealed that the trainees’ scores at T1 and T2 were significantly higher than those at T0（P<0.05）. Moreover，operational skills and self-efficacy scores at T2 were significantly higher than those at T1（P<0.05）. Conclusion The ex-vivo porcine lung bionic simulation system is feasible for mechanical ventilator training in the emergency department. It effectively enhances trainees’ theoretical knowledge，operational proficiency，and professional self-efficacy. This study can provide a reference for optimizing training programs for emergency department nurses.