目的 以硝酸甘油口服片为例，设计基于证据的老年患者用药指导（Patient Medication Guide，PMG）工具，评价其正确性、全面性与可读性。 方法 在调查老年患者PMG应用现状与需求的基础上初步确定内容主题，经证据总结和外部评审确定最佳证据并进行证据细化，基于情感化设计三层次理论进行证据转化，最终形成硝酸甘油片老年PMG工具。邀请临床医务人员评价该PMG内容的全面性和准确性；招募老年硝酸甘油口服片用药患者等相关人员，采用健康教育文本材料适用性量表（Suitability Assessment of Materials，SAM）进行可读性评价。 结果 形成包括适应证、禁忌证、用法用量、不良反应、药效监测、药物配伍、药物与饮食的关系、储存方法8个主题、22个细化主题的老年PMG工具。52名医务人员认为该PMG内容的正确性、全面性的平均得分率均>90%；受试对象（n=105）的SAM平均得分率均值为94.94%。 结论 硝酸甘油口服片老年PMG工具具有可读性良好、内容全面准确的特点，得到了医务人员和患者的认可，具有推广价值。

Objective To design an evidence-based Patient Medication Guide（PMG） tool for elderly patients and evaluate its correctness，comprehensiveness，and readability through the example of using nitroglycerin oral tablets. Methods The content themes were preliminarily identified based on an investigation of the current application status and needs of PMG among elderly patients. Best practices were determined through evidence synthesis and external review，followed by evidence refinement. After that，guided by the three-level theory of emotional design，the evidence was translated into practical applications and ultimately forming the elderly PMG tool for nitroglycerin tablets. In evaluation，clinical healthcare professionals were invited to assess the comprehensiveness and accuracy of the PMG content. Elderly patients using nitroglycerin oral tablets and relevant stakeholders were recruited to assess the readability using the Suitability Assessment of Materials （SAM） scale for health education text materials. Results A PMG was formed，including 8 themes and 22 detailed themes such as indications，contraindications，dosage and administration，adverse reactions，drug efficacy monitoring，drug compatibility，the relationship between drugs and diet，and storage methods. The average score rate of correctness and comprehensiveness of the PMG content by 52 medical staff was over 90% and the average score rate of 105 research participants was 94.94%. Conclusion The PMG for elderly patients using nitroglycerin oral tablets designed in this study holds good readability and comprehensive and accurate content，which are recognized by medical staff and patients with apllication value.