收稿日期: 2024-03-03
网络出版日期: 2024-12-17
基金资助
浙江省医药卫生科技计划(2024KY1058);浙江省中医药科技项目(2024ZL568)
The incidence and related factors of apathy in Chinese stroke patients：a meta analysis
目的 系统评价国内脑卒中患者淡漠发生率及其相关因素。方法 计算机检索PubMed、Embase、Web of Science、Cochrane Library、中国生物医学文献数据库、中国知网、维普和万方数据库，研究对象为国内脑卒中患者的淡漠发生率和（或）其相关因素的研究，检索时限为建库至2024年1月。由2名研究人员独立筛选文献、提取资料并进行质量评价，采用Stata 12.0和RevMan 5.3软件进行数据分析。结果 共纳入20篇文献，包括3 135例患者。Meta分析结果显示，脑卒中患者淡漠发生率为35.0%。卒中史（OR=2.75）、糖尿病（OR=2.39）、美国国立卫生研究院卒中量表（National Institute of Health Stroke Scale，NIHSS）评分（OR=1.27）、认知功能（OR=0.80）、日常生活活动能力（OR=0.87）、抑郁（OR=1.14）、同型半胱氨酸（OR=1.17）、多病灶（OR=13.24）、额叶病变（OR=10.25）、脑干部位病变（OR=11.65）、脑桥病变（OR=3.92）、基底节病变（OR=5.26）为脑卒中患者淡漠的影响因素（均P<0.05）。结论 脑卒中患者淡漠发生率较高且影响因素众多，医护人员应对高危人群着重关注，及早采取相关干预措施。
杨红燕 , 柳妙妙 , 魏慧 , 杨婷 , 高杨琴 , 杨玲虹 , 兰美娟 . 国内脑卒中患者淡漠发生率及相关因素的Meta分析[J]. 中华护理教育, 2024 , 21(12) : 1517 -1522 . DOI: 10.3761/j.issn.1672-9234.2024.12.018
Objective To systematically evaluate the incidence and related factors of apathy in Chinese stroke patients. Methods We searched PubMed，Embase，Web of Science，Cochrane Library，China Biomedical Literature Database，CNKI，VIP，and Wanfang databases for studies on the incidence of apathy in Chinese stroke patients and/or its related factors，with a search deadline from inception to January 2024. Two researchers independently screened the literature，extracted data，and assessed the bias risk. Data analysis was performed using Stata 12.0 and RevMan 5.3 software. Results A total of 20 articles involving 3，135 patients were included. Meta analysis results showed that the incidence of apathy in Chinese stroke patients was 35.0%. The influencing factors for apathy in stroke patients included a stroke history（OR=2.75），diabetes（OR=2.39），NIHSS score（OR=1.27），cognitive function（OR=0.80），activity of daily living（OR=0.87），depression（OR=1.14），homocysteine（OR=1.17），multiple lesions（OR=13.24），frontal lobe lesions（OR=10.25），brain stem lesions（OR=11.65），pontine lesions（OR=3.92），basal ganglia lesions（OR=5.26）（all P<0.05）. Conclusion The incidence of apathy in stroke patients in China is relatively high and there are many influencing factors. Medical staffs should pay special attention to high-risk populations and take early relevant intervention measures.
Key words： Stroke; Apathy; Prevalence; Related factors; Meta-analysis
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