目的 探讨放射医学工程与护理交叉前沿课程的教学设计与实践效果，为学科交叉融合背景下护理专业人才的培养提供参考。 方法 通过确立教学目标、明确教学内容与方法、设计课程考核与评价，构建放射医学工程与护理交叉前沿课程的教学方案。2023学年—2024学年秋季学期，将教学方案应用于选修该课程的26名大学二年级护理专业本科生中。课程结束后，通过自设问卷了解学生对教学安排、内容、方法、效果等的看法及其建议。 结果 26名学生课程成绩为（91.5±3.2）分。问卷调查结果显示，73%（19/26）的学生认为本课程教师教学效果非常好；96%（25/26）的学生认为对本课程的学习效果非常好或比较好，58%（15/26）的学生表示本课程在培养跨学科思维和解决护理学难点问题上的效果显著；分别有54%（14/26）、50%（13/26）的学生表示本课程在案例分析、小组讨论方面的教学效果有待改进；65%（17/26）的学生建议通过引入案例研究和模拟实践环节，提升其参与度。 结论 放射医学工程与护理交叉前沿课程教学取得了良好的效果，有效培养了护理专业学生的跨学科思维，但仍需结合学生的反馈从内容、方法等方面对教学进行深度优化，以进一步提升实践成效。

Objective To explore the teaching design and practical effect of the Cross Frontier of Radiation Medicine Engineering and Nursing，so as to provide references for the construction of the multidisciplinary intersection training for nursing undergraduates in China. Methods A teaching plan for Cross Frontier of Radiation Medicine Engineering and Nursing was designed after defining teaching objectives，clarifying teaching contents and methods，and designing teaching evaluations. During the fall semester of 2023-2024 academic year，this teaching plan was applied among 26 second-year undergraduate nursing students who selected the course. After the course，a self-designed questionnaire was used to collect students’ opinions and suggestions on the teaching arrangement，content，and effect. Results The average course score among the 26 students was（91.5±3.2） points. According to the questionnaire results，73%（19/26） of the students believed that the teaching effect of the course teachers were excellent；96%（25/26） reported that their learning outcomes in this course were very good or relatively good，and 58%（15/26） indicated that the course has significantly enhanced their interdisciplinary thinking and ability to solve challenging nursing problems. Still，54%（14/26） and 50%（13/26） of the students suggested that the teaching effects in case analysis and group discussions required further improvement. Additionally，65%（17/26） of the students recommended enhancing their engagement through the introduction of case studies and simulated practice sessions. Conclusion The teaching of the Cross Frontier of Radiation Medicine Engineering and Nursing can achieve promising results，effectively fostering interdisciplinary thinking among nursing students. However，it is necessary to integrate student feedback and conduct further optimization of the course content，methodologies，and other aspects to further enhance its practical effect.