目的 了解内蒙古三级甲等医院高年资护士职业生涯成功水平现状，并分析其影响因素。方法 于2021年12月—2022年3月，采用一般资料调查表、职业生涯成功量表对3 317名内蒙古三级甲等医院高年资护士进行问卷调查。结果 共回收有效问卷3 088份。3 088名高年资护士职业生涯成功得分为（31.22±6.70）分；多元线性逐步回归分析结果显示，科室为儿科（以内科为参照）、工资待遇满意度、身体状况、院外进修培训情况、参与科研项目情况、对自身工作状态的满意程度、对未来职业发展的担忧情况、有无职业生涯规划、最想去的科室或岗位为行政科室（以无为参照）或辅助科室（以无为参照）、工作中最大的挑战为职业发展不明确（以体力不足为参照）或对领导方式不满意（以体力不足为参照）为内蒙古三级甲等医院高年资护士职业生涯成功水平的影响因素（P<0.05），共解释职业生涯成功水平25.7%的变异度。结论 内蒙古三级甲等医院高年资护士职业生涯成功处于中等偏下水平，且受多种因素影响。护理管理者应关注高年资护士群体，针对其职业生涯成功水平影响因素精准施策，进而提高其职业生涯成功水平。

Objective To investigate the career success status of senior nurses in tertiary hospitals in Inner Mongolia Autonomous Region，and to analyze its influencing factors. Methods From December 2021 to March 2022，a self-designed general information questionnaire and career success scale were used to survey 3 088 senior nurses in tertiary hospitals in Inner Mongolia Autonomous Region. Results The career success scores of 3 088 senior nurses were（31.22±6.70），and the results of multiple linear stepwise regression analysis showed that pediatrics （with internal medicine as a reference），salary satisfaction，physical condition，the situation of external training and education，career planning，satisfaction with their work status，worries about future career development，experience of participating in scientific research projects，the department or position they most want to go was administrative departments （with none as a reference） or auxiliary departments（with none as a reference），and the biggest challenge in the work was unclear career development （with insufficient physical strength as a reference） or dissatisfaction with leadership style （with insufficient physical strength as a reference） were the influencing factors of the career success score of senior nurses（P<0.05），which explained 25.7% of the total variation. Conclusion The career success level of senior nurses in Inner Mongolia tertiary hospitals needs to be improved，and it is affected by various factors. Nursing managers should pay attention to the group of senior nurses and implement targeted measures to address the factors that affect their career success level，thereby improving their career success level.