目的 总结子痫前期预防的最佳证据。 方法 系统检索国内外决策支持系统、数据库及指南或专业协会网站中关于子痫前期预防的文献，检索时限为2013年1月—2023年1月，文献类型包括临床决策、指南、最佳实践、证据总结、系统评价、专家共识。由2名研究者独立筛选文献、提取资料并对纳入文献的方法学质量进行评价后，对证据进行提取、质量分级及汇总。 结果 共纳入24篇文献，其中临床决策2篇、指南8篇、专家共识3篇、系统评价11篇。从风险因素、风险评估时机与方法、血压监测与管理、药物预防、非药物预防、健康教育6个方面总结出21条关于子痫前期预防的最佳证据。 结论 本研究总结了子痫前期预防的最佳证据。医护人员应结合临床情境、孕妇意愿，审慎地选择与运用证据，以早期甄别高危孕妇，并指导其早期开展子痫前期预防工作，进而降低其子痫前期的发生风险，促进母婴安全。

Objective To search and summarize the best evidence of preeclampsia prevention in pregnant women. Methods The relevant evidence of preeclampsia prevention in pregnant women was systematically searched from domestic and foreign databases. The retrieval time was from June 1, 2013 to June 1, 2023. Clinical decisions, guidelines, evidence summaries, systematic evaluations and expert consensuses were included. Two researchers independently screened literature, extracted data, and evaluated the quality of the included literature. The evidence was extracted from the included literature and summarized after its quality was graded. Results A total of 24 articles were enrolled, including two clinical decision, eight guidelines, three expert consensuses, and 11 systematic reviews. Then 21 pieces of evidence were summarized, including risk factors, timing and tools for risk factor assessment, blood pressure monitoring and management, drug prevention, non-drug prevention, and health education. Conclusion This study summarized the measures to prevent preeclampsia for pregnant women. Evidence should be carefully selected in combination with the clinical situation in China and the wishes of pregnant women, so as to early identify high-risk pregnant women and carry out early prevention, so as to reduce the risk of preeclampsia and promote the safety of mother and child.