目的 探讨临床护士反思性实践对其用药安全能力的影响，为护士安全用药能力培养提供依据。 方法 本研究为横断面研究，采用便利抽样法，于2022年选取郑州市5所三级甲等医院的临床护士为研究对象，分别采用一般资料问卷、中文版反思性实践问卷、中文版用药安全能力量表对其调查。 结果 回收有效问卷1 127份，有效回收率为87.16%。护士反思性实践量表总分为（128.97±16.07）分，用药安全能力量表总分为（138.39±25.13）分；Pearson相关性分析显示，反思性实践与用药安全能力呈正相关（r=0.579，P<0.001）；多重线性回归分析显示，反思性实践是临床护士用药安全能力的影响因素（β=0.577，P<0.001），可独立解释33.2%的变异（F=150.674，P<0.001）。 结论 反思性实践对临床护士用药安全能力有正向影响，可通过增进反思性实践提高临床护士的用药安全能力。

Objective To explore the impact of clinical nurses’ reflective practice on their medication safety competence，and provide reference for cultivating nurses’ medication safety competence. Methods Cross-sectional study design was adopted by convenient sampling. In 2022，clinical nurses from five grade Ⅲ hospitals in Zhengzhou were recruited and investigated by the general information questionnaire，the Chinese version of the Reflective Practice Questionnaire，and the Chinese version of the Medication Safety Competence Scale. Results A total of 1 127 valid questionnaires were collected，with the effective recovery rate was 87.16%. The total score of the nurses’ reflective practice was（128.97±16.07），and the total score of the medication safety competence was （138.39±25.13）. Pearson correlation analysis showed that reflective practice was positively correlated with medication safety competence（r=0.579，P<0.001）. Multiple linear regression analysis found that reflective practice was the influencing factor of clinical nurses’ medication safety competence（β=0.577，P<0.001），explaining 33.2% of the total variation（F=150.674, P<0.001） independently. Conclusion Reflective practice has a positive impact on the ability of clinical nurses to use drug safely，which could be improved by enhancing reflective practice.