目的 探讨影响母婴分离的早产产妇泌乳Ⅱ期启动延迟（Delayed Onset of Lactogenesis Ⅱ,DOL Ⅱ）的因素。 方法 采用便利抽样法,对300例母婴分离的早产产妇的泌乳Ⅱ期启动时间进行跟踪测定,并采用自行设计的母婴分离的早产产妇泌乳Ⅱ期启动时间相关因素调查表进行调查。 结果 母婴分离的早产产妇DOL Ⅱ的发生率为35.67%,影响其DOL Ⅱ的因素为孕期BMI增幅及合并妊娠高血压综合征;孕期BMI增幅≥7.2 kg/m ²与妊娠高血压综合征对DOL Ⅱ的发生风险存在正向交互作用（OR=27.772,95%CI：12.046~64.030）。 结论 妊娠高血压综合征及孕期BMI增幅是影响母婴分离的早产产妇DOL Ⅱ的重要因素,且孕期BMI增幅与妊娠高血压综合征的交互作用增加了DOL Ⅱ的发生风险,医护人员及孕妇应高度重视孕妇BMI及血压变化,及时控制其孕期体重及血压的增长幅度,以预防DOL Ⅱ,改善早期泌乳状况。

Objective To investigate the related factors of delayed onset of lactogenesis Ⅱ（DOL Ⅱ） in preterm parturient women separated from their infants. Methods The convenience sampling was used to track and measure the start time of lactation Ⅱ in 300 cases of preterm delivery women separated from their infants,and the influencing factors of DOL Ⅱ were investigated by using the questionnaire of factors related to the start time of lactation Ⅱ in preterm delivery women separated from their infants. Results The incidence of DOL Ⅱ in preterm mothers separated from their infants was 35.67%,and the factors influencing DOL Ⅱ were the increase of Body Mass Index（BMI） during pregnancy and pregnancy hypertension syndrome. There is a positive interaction between pregnancy induced hypertension and BMI increase≥7.2 kg/m ² during pregnancy on the risk of DOL Ⅱ（OR=27.772,95%CI：12.046~64.030）. Conclusion Preeclampsia and the increase of BMI during pregnancy are important factors affecting DOL Ⅱ of the preterm parturient women separated from their infants,and the interaction between the increase of BMI during pregnancy and the preeclampsia increases the risk of DOL Ⅱ occurrence. Medical staff and pregnant women should pay great attention to prenatal BMI and blood pressure changes,timely control in the growth of body weight and blood pressure during pregnancy,in order to prevent the DOL Ⅱ,and improve the early lactation.