目的 总结、评价国内外关于慢性阻塞性肺疾病患者氧疗管理的最佳证据,为临床护理人员提供循证依据。方法 检索UpToDate、PubMed、Cochrane Library、英国国家健康和保健医学研究所、国际指南网、慢性阻塞性肺疾病全球倡议官网、爱尔兰胸科协会、澳大利亚肺基金会、欧洲呼吸协会、中华护理学会、万方数据库、中国知网等的相关文献。采用AGREE Ⅱ和澳大利亚JBI循证卫生保健中心对应的评价标准（2016版）对文献进行质量评价,并进行证据提取、汇总和分析。 结果 共纳入14篇文献,其中10篇指南、2篇证据总结、1篇系统评价及1篇行业标准。最终形成了包括氧疗评估、氧疗方式、氧流量及氧疗时长、长期氧疗、健康教育和出院随访共23条慢性阻塞性肺疾病患者氧疗管理的最佳证据。 结论 本研究总结了来自多个国家的慢性阻塞性肺疾病氧疗管理的最佳证据,可为护理人员制订科学的干预方案提供依据。在应用前应进行临床环境及其他相关因素的评估,以促进护理质量的提升。

Objective To search,evaluate and integrate the best evidence of oxygen therapy management in patients with chronic obstructive pulmonary disease（COPD）,so as to provide basis for formulating the management standard of patients’ oxygen therapy. Methods The databases were searched including UpToDate,PubMed,Cochrane Library,National Institute for Health and Care Excellence,Guidelines International Network,Global Initiative for Chronic Obstructive Lung Disease,Irish Thoracic Association,Australian Lung Foundation,European Respiratory Association,Chinese Nursing Society,Wanfang Database,CNKI,et al. We used AGREE Ⅱ and JBI evidence-based health care center’s document quality evaluation standard and evidence recommendation system（2016 version） to evaluate the quality of various studies and the level of evidence recommendation.The evidence was extracted,summarized and analyzed. Results A total of 14 articles were included,including 10 guidelines,2 evidence summaries,1 systematic review and 1 industy standard. Finally,23 best evidences were summarized including oxygen therapy evaluation,oxygen therapy methods,oxygen flow and duration of oxygen therapy,long-term oxygen therapy,health education and discharge follow-up. Conclusion This study summarizes the best evidence of oxygen therapy for COPD,which can provide a scientific basis for nurses to manage oxygen therapy for patients with COPD. Since the evidence summarized in this study comes from many countries,the personnel also need to continuously update the evidence to improve the hospital safety management by applying the best evidence.