中华护理教育 ›› 2020, Vol. 17 ›› Issue (3): 268-274.doi: 10.3761/j.issn.1672-9234.2020.03.017
收稿日期:
2019-10-11
出版日期:
2020-03-20
发布日期:
2020-03-07
通讯作者:
王艳红
作者简介:
迟俊婷,女,本科(硕士在读),护士,E-mail: chijt18@lzu.edu.cn
基金资助:
CHI Jun-ting,NIU Xiao-dan,RUAN Hai-hui,TAO Hong-xia,ZHANG Jing,WANG Yan-hong()
Received:
2019-10-11
Online:
2020-03-20
Published:
2020-03-07
Contact:
Yan-hong WANG
摘要:
目的 明确潜在不适当用药对老年人不良健康结局的影响,为预防不良健康结局提供依据。方法 检索PubMed、The Cochrane Library、Web of Science、EMBASE、中国生物医学文献数据库、中国知网和万方数据库,搜集建库至2019年2月关于潜在不适当用药对老年人不良健康结局影响的文献,采用RevMan 5.3软件进行分析。结果 共纳入33项队列研究,结果显示潜在不适当用药对药物不良反应、再次入院率有影响(RR=1.69,95%CI=1.28~2.23,P<0.001;RR=1.47,95%CI=1.30~1.66,P<0.001),但不会增加死亡率(RR=1.02,95%CI=0.98~1.07,P=0.310)。结论 潜在不适当用药是老年人发生药物不良反应/药物不良事件和再次入院的危险因素,增加了社会经济负担,耗费了医疗资源。
迟俊婷, 牛晓丹, 阮海慧, 陶红霞, 张静, 王艳红. 潜在不适当用药对老年人不良健康结局影响的系统评价[J]. 中华护理教育, 2020, 17(3): 268-274.
CHI Jun-ting, NIU Xiao-dan, RUAN Hai-hui, TAO Hong-xia, ZHANG Jing, WANG Yan-hong. The relationship between potentially inappropriate medications use and adverse health outcomes in the older adults:a systematic review[J]. Chinese Journal of Nursing Education, 2020, 17(3): 268-274.
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