中华护理教育 ›› 2021, Vol. 18 ›› Issue (12): 1098-1105.doi: 10.3761/j.issn.1672-9234.2021.12.007
收稿日期:
2021-03-02
出版日期:
2021-12-20
发布日期:
2021-12-27
通讯作者:
万巧琴
作者简介:
赵小燕:女,本科(硕士在读),E-mail: 基金资助:
ZHAO Xiao-yan(),HUANG Xiu-xiu,WAN Qiao-qin()
Received:
2021-03-02
Online:
2021-12-20
Published:
2021-12-27
Contact:
Qiao-qin WAN
摘要:
目的 了解国内外运动结合认知训练在轻度认知障碍和阿尔茨海默病患者中应用的研究现状。方法 根据Whittemore和Knafl提出的整合性综述框架对相关文献进行整合。结果 最终纳入33篇文献,对应28项研究。轻度认知障碍和阿尔茨海默病患者的运动与认知训练的结合模式分为三类:双任务式、交互式和序贯式。双任务式的干预周期最长,干预形式较为简单;交互式与双任务式较为相似,干预形式多为有氧运动结合电脑游戏;序贯式周干预持续时间最长,干预频次最多,运动和认知训练形式比较复杂。此外,在设置对照组的25项研究中,18项研究(72.0%)是双臂研究;13项研究(46.4%)报道了依从率。效果评价指标包括认知功能、精神行为症状、日常生活活动能力、生活质量、步态等。结论 轻度认知障碍和阿尔茨海默病患者的运动结合认知训练方案有待进一步规范化,建议未来研究设置合理的对照组,关注依从性,并结合客观指标探究其作用效果及路径。
赵小燕,黄秀秀,万巧琴. 运动结合认知训练在轻度认知障碍和阿尔茨海默病患者中应用的整合性综述[J]. 中华护理教育, 2021, 18(12): 1098-1105.
ZHAO Xiao-yan,HUANG Xiu-xiu,WAN Qiao-qin. The effects of exercise combined with cognitive training in people with mild cognitive impairment and Alzheimer’s disease:an integrated review[J]. Chinese Journal of Nursing Education, 2021, 18(12): 1098-1105.
[1] |
2020 Alzheimer's disease facts and figures[J]. Alzheimers Dement, 2020, 16(3):391-460.
doi: 10.1002/alz.v16.3 |
[2] |
Coelho FG, Andrade LP, Pedroso RV, et al. Multimodal exercise intervention improves frontal cognitive functions and gait in Alzheimer’s disease:a controlled trial[J]. Geriatr Gerontol Int, 2013, 13(1):198-203.
doi: 10.1111/ggi.2013.13.issue-1 |
[3] |
Yoon JE, Lee SM, Lim HS, et al. The effects of cognitive activity combined with active extremity exercise on balance,walking activity,memory level and quality of life of an older adult sample with dementia[J]. J Phys Ther Sci, 2013, 25(12):1601-1604.
doi: 10.1589/jpts.25.1601 |
[4] |
Anderson-Hanley C, Barcelos NM, Zimmerman EA, et al. The aerobic and cognitive exercise study(ACES) for community-dwelling older adults with or at-risk for mild cognitive impairment(MCI):neuropsychological,neurobiological and neuroimaging outcomes of a randomized clinical trial[J]. Front Aging Neurosci, 2018, 10:76.
doi: 10.3389/fnagi.2018.00076 pmid: 29780318 |
[5] | 杨思兰, 张杰, 李娟, 等. 整合性综述及其在国外护理领域的应用进展[J]. 解放军护理杂志, 2020, 37(7):54-57. |
Yang SL, Zhang J, Li J, et al. Integrative review and application progress at abroad in nursing field[J]. Nurs J Chin PLA, 2020, 37(7):54-57. | |
[6] |
Schwenk M, Zieschang T, Oster P, et al. Dual-task performances can be improved in patients with dementia:a randomized controlled trial[J]. Neurology, 2010, 74(24):1961-1968.
doi: 10.1212/WNL.0b013e3181e39696 |
[7] |
Kounti F, Bakoglidou E, Agogiatou C, et al. RHEA,a nonpharmacological cognitive training intervention in patients with mild cognitive impairment:a pilot study[J]. Top Geriatr Rehabil, 2011, 27(4):289-300.
doi: 10.1097/TGR.0b013e31821e59a9 |
[8] |
Suzuki T, Shimada H, Makizako H, et al. Effects of multicomponent exercise on cognitive function in older adults with am-nestic mild cognitive impairment:a randomized controlled trial[J]. BMC Neurol, 2012, 12:128.
doi: 10.1186/1471-2377-12-128 pmid: 23113898 |
[9] |
de Andrade LP, Gobbi LT, Coelho FG, et al. Benefits of multimodal exercise intervention for postural control and frontal cognitive functions in individuals with Alzheimer’s disease:a controlled trial[J]. J Am Geriatr Soc, 2013, 61(11):1919-1926.
doi: 10.1111/jgs.12531 |
[10] |
Suzuki T, Shimada H, Makizako H, et al. A randomized controlled trial of multicomponent exercise in older adults with mild cognitive impairment[J]. PLoS One, 2013, 8(4):e61483.
doi: 10.1371/journal.pone.0061483 |
[11] |
Venturelli M, Sollima A, Cè E, et al. Effectiveness of exercise and cognitive-based treatments on salivary cortisol levels and sundowning syndrome symptoms in patients with Alzheimer’s disease[J]. J Alzheimers Dis, 2016, 53(4):1631-1640.
doi: 10.3233/JAD-160392 pmid: 27540967 |
[12] | Combourieu Donnezan L, Perrot A, Belleville S, et al. Effects of simultaneous aerobic and cognitive training on executive functions,cardiovascular fitness and functional abilities in older adults with mild cognitive impairment[J]. Ment Heal Phys Activity, 2018, 15:78-87. |
[13] |
Okamura H, Otani M, Shimoyama N, et al. Combined exercise and cognitive training system for dementia patients:a randomized controlled trial[J]. Dement Geriatr Cogn Disord, 2018, 45(5/6):318-325.
doi: 10.1159/000490613 |
[14] | Jeong MK, Lee SH, Ryu JK, et al. Effects of long-term multi-task exercise program on blood pressure,physical function and cognitive function in mild cognitive impairment elderly women with hypertension[J/OL]. (2019-04-11). Archives of Budo. http://archbudo.com/ . |
[15] |
Shimada H, Makizako H, Doi T, et al. Effects of combined physical and cognitive exercises on cognition and mobility in patients with mild cognitive impairment:a randomized clinical trial[J]. J Am Med Dir Assoc, 2018, 19(7):584-591.
doi: 10.1016/j.jamda.2017.09.019 |
[16] | Park H, Park JH, Na HR, et al. Combined intervention of physical activity,aerobic exercise,and cognitive exercise intervention to prevent cognitive decline for patients with mild cognitive impairment:a randomized controlled clinical study[J]. J Clin Med, 2019, 8(7):E940. |
[17] |
Ben-Sadoun G, Sacco G, Manera V, et al. Physical and cognitive stimulation using an exergame in subjects with normal aging,mild and moderate cognitive impairment[J]. J Alzheimers Dis, 2016, 53(4):1299-1314.
doi: 10.3233/JAD-160268 pmid: 27372645 |
[18] |
Mrakic-Sposta S, di Santo SG, Franchini F, et al. Effects of combined physical and cognitive virtual reality-based training on cognitive impairment and oxidative stress in MCI patients:a pilot study[J]. Front Aging Neurosci, 2018, 10:282.
doi: 10.3389/fnagi.2018.00282 pmid: 30327596 |
[19] | Wall K, Stark J, Schillaci A, et al. The enhanced interactive physical and cognitive exercise system(iPACESTM v2.0):pilot clinical trial of an in-home iPad-based neuro-exergame for mild cognitive impairment(MCI)[J]. J Clin Med, 2018, 7(9):E249. |
[20] |
Werner C, Rosner R, Wiloth S, et al. Time course of changes in motor-cognitive exergame performances during task-specific training in patients with dementia:identification and predictors of early training response[J]. J NeuroEng Rehabil, 2018, 15(1):100.
doi: 10.1186/s12984-018-0433-4 |
[21] | Wiloth S, Werner C, Lemke NC, et al. Motor-cognitive effects of a computerized game-based training method in people with dementia:a randomized controlled trial[J]. Aging Ment Health, 2018, 22(9):1124-1135. |
[22] |
Karssemeijer EGA, Aaronson JA, Bossers WJR, et al. The quest for synergy between physical exercise and cognitive stimulation via exergaming in people with dementia:a randomized controlled trial[J]. Alzheimers Res Ther, 2019, 11(1):3.
doi: 10.1186/s13195-018-0454-z pmid: 30611286 |
[23] |
Karssemeijer EGA, Bossers WJR, Aaronson JA, et al. Exergaming as a physical exercise strategy reduces frailty in people with dementia:a randomized controlled trial[J]. J Am Med Dir Assoc, 2019, 20(12):1502-1508.e1.
doi: S1525-8610(19)30522-5 pmid: 31409559 |
[24] |
Liao YY, Chen IH, Lin YJ, et al. Effects of virtual reality-based physical and cognitive training on executive function and dual-task gait performance in older adults with mild cognitive impairment:a randomized control trial[J]. Front Aging Neurosci, 2019, 11:162.
doi: 10.3389/fnagi.2019.00162 |
[25] | Liao YY, Tseng HY, Lin YJ, et al. Using virtual reality-based training to improve cognitive function,instrumental activities of daily living and neural efficiency in older adults with mild cognitive impairment[J]. Eur J Phys Rehabil Med, 2020, 56(1):47-57. |
[26] |
Fiatarone Singh MA, Gates N, Saigal N, et al. The Study of Mental and Resistance Training(SMART)study—resistance training and/or cognitive training in mild cognitive impairment:a randomized,double-blind,double-sham controlled trial[J]. J Am Med Dir Assoc, 2014, 15(12):873-880.
doi: 10.1016/j.jamda.2014.09.010 pmid: 25444575 |
[27] |
Suo C, Singh MF, Gates N, et al. Therapeutically relevant structural and functional mechanisms triggered by physical and cognitive exercise[J]. Mol Psychiatry, 2016, 21(11):1645.
doi: 10.1038/mp.2016.57 |
[28] |
González-Palau F, Franco M, Bamidis P, et al. The effects of a computer-based cognitive and physical training program in a healthy and mildly cognitive impaired aging sample[J]. Aging Ment Health, 2014, 18(7):838-846.
doi: 10.1080/13607863.2014.899972 pmid: 24697325 |
[29] | Styliadis C, Kartsidis P, Paraskevopoulos E, et al. Neuroplastic effects of combined computerized physical and cognitive training in elderly individuals at risk for dementia:an eLORETA controlled study on resting states[J]. Neural Plast, 2015, 2015:172192. |
[30] |
Hagovská M, Olekszyová Z. Impact of the combination of cognitive and balance training on gait,fear and risk of falling and quality of life in seniors with mild cognitive impairment[J]. Geriatr Gerontol Int, 2016, 16(9):1043-1050.
doi: 10.1111/ggi.12593 |
[31] | Hagovská M, Takáć P, Dzvoník O. Effect of a combining cognitive and balanced training on the cognitive,postural and functional status of seniors with a mild cognitive deficit in a randomized,controlled trial[J]. Eur J Phys Rehabil Med, 2016, 52(1):101-109. |
[32] | Klados MA, Styliadis C, Frantzidis CA, et al. Beta-band functional connectivity is reorganized in mild cognitive impairment after combined computerized physical and cognitive training[J]. Front Neurosci, 2016, 10:55. |
[33] |
Damirchi A, Hosseini F, Babaei P. Mental training enhances cognitive function and BDNF more than either physical or combined training in elderly women with MCI:a small-scale study[J]. Am J Alzheimers Dis Other Demen, 2018, 33(1):20-29.
doi: 10.1177/1533317517727068 |
[34] | 蔡俊, 张忠兴. 功能性锻炼结合认知训练对老年轻度认知障碍患者认知功能影响研究[J]. 牡丹江师范学院学报(自然科学版), 2019(2):43-47. |
Cai J, Zhang ZX. Effect of functional exercise combined with cognitive training on cognitive function in old patients with cognitive impairment[J]. J Mudanjiang Norm Univ Nat Sci Ed, 2019(2):43-47. | |
[35] | 张杰. 有氧运动联合计算机认知训练对轻度认知障碍患者认知功能的影响[J]. 中国实用护理杂志, 2019, 35(34):2653-2657. |
Zhang J. The impact of aerobic exercise combined and computer cognitive training on cognitive function in patients with mild cognitive impairment[J]. Chin J Pract Nurs, 2019, 35(34):2653-2657. | |
[36] | WHO. Physical activity and older adults[EB/OL].[2021-06-24]. https://www.who.int/ncds/prevention/physical-activity/factsheet_olderadults/en/ . |
[37] |
Lauenroth A, Ioannidis AE, Teichmann B. Influence of combined physical and cognitive training on cognition:a systematic review[J]. BMC Geriatr, 2016, 16:141.
doi: 10.1186/s12877-016-0315-1 pmid: 27431673 |
[38] |
Gheysen F, Poppe L, DeSmet A, et al. Physical activity to improve cognition in older adults:can physical activity programs enriched with cognitive challenges enhance the effects?A systematic review and meta-analysis[J]. Int J Behav Nutr Phys Act, 2018, 15(1):63.
doi: 10.1186/s12966-018-0697-x pmid: 29973193 |
[39] | 赵景茹, 吕佩源. 2017年AAN轻度认知功能障碍实践指南解读[J]. 中国全科医学, 2018, 21(12):1387-1391. |
Zhao JR, Lyu PY. Interpretation of the 2017 AAN practice guideline for mild cognitive impairment[J]. Chin Gen Pract, 2018, 21(12):1387-1391. | |
[40] |
Karssemeijer EGA, Aaronson JA, Bossers WJ, et al. Positive effects of combined cognitive and physical exercise training on cognitive function in older adults with mild cognitive impairment or dementia:a meta-analysis[J]. Ageing Res Rev, 2017, 40:75-83.
doi: S1568-1637(17)30114-9 pmid: 28912076 |
[41] |
Xu ZJ, Sun W, Zhang DX, et al. Recruitment and adherence of randomized controlled trials for mild cognitive impairment:a systematic review and meta-analysis[J]. Int J Geriatr Psychiatry, 2020, 35(10):1141-1150.
doi: 10.1002/gps.v35.10 |
[42] |
Tian Q, Resnick SM, Mielke MM, et al. Association of dual decline in memory and gait speed with risk for dementia among adults older than 60 years:a multicohort individual-level meta-analysis[J]. JAMA Netw Open, 2020, 3(2):e1921636.
doi: 10.1001/jamanetworkopen.2019.21636 |
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